RADON (Rn)
The most common source of indoor radon is uranium in the soil or rock on which homes are built. As uranium naturally breaks down, it releases radon gas which is a colorless, odorless, radioactive gas. Radon gas enters homes through dirt floors, cracks in concrete walls and floors, floor drains, and sumps. When radon becomes trapped in buildings and concentrations build up indoors, exposure to radon becomes a concern.

Any home may have a radon problem. This means new and old homes, well-sealed and drafty homes, and homes with or without basements. Sometimes radon enters the home through well water. In a small number of homes, the building materials can give off radon, too. However, building materials rarely cause radon problems by themselves.

Health Effects of Radon
The predominant health effect associated with exposure to elevated levels of radon is lung cancer. Research suggests that swallowing water with high radon levels may pose risks, too, although these are believed to be much lower than those from breathing air containing radon. Major health organizations (like the Centers for Disease Control and Prevention, the American Lung Association (ALA), and the American Medical Association) agree with estimates that radon causes thousands of preventable lung cancer deaths each year. EPA estimates that radon causes about 14,000 deaths per year in the United States--however, this number could range from 7,000 to 30,000 deaths per year. If you smoke and your home has high radon levels, your risk of lung cancer is especially high.

ENVIRONMENTAL TOBACCO SMOKE (ETS)
Environmental tobacco smoke (ETS) is the mixture of smoke that comes from the burning end of a cigarette, pipe, or cigar, and smoke exhaled by the smoker. It is a complex mixture of over 4,000 compounds, more than 40 of which are known to cause cancer in humans or animals and many of which are strong irritants. ETS is often referred to as "secondhand smoke" and exposure to ETS is often called "passive smoking."

Health Effects of Environmental Tobacco Smoke
In 1992, EPA completed a major assessment of the respiratory health risks of ETS (Respiratory Health Effects of Passive Smoking: Lung Cancer and Other Disorders EPA/600/6-90/006F). The report concludes that exposure to ETS is responsible for approximately 3,000 lung cancer deaths each year in nonsmoking adults and impairs the respiratory health of hundreds of thousands of children.

Infants and young children whose parents smoke in their presence are at increased risk of lower respiratory tract infections (pneumonia and bronchitis) and are more likely to have symptoms of respiratory irritation like cough, excess phlegm, and wheeze. EPA estimates that passive smoking annually causes between 150,000 and 300,000 lower respiratory tract infections in infants and children under 18 months of age, resulting in between 7,500 and 15,000 hospitalizations each year. These children may also have a build-up of fluid in the middle ear, which can lead to ear infections. Older children who have been exposed to secondhand smoke may have slightly reduced lung function.

Asthmatic children are especially at risk. EPA estimates that exposure to secondhand smoke increases the number of episodes and severity of symptoms in hundreds of thousands of asthmatic children, and may cause thousands of non-asthmatic children to develop the disease each year. EPA estimates that between 200,000 and 1,000,000 asthmatic children have their condition made worse by exposure to secondhand smoke each year. Exposure to secondhand smoke causes eye, nose, and throat irritation. It may affect the cardiovascular system and some studies have linked exposure to secondhand smoke with the onset of chest pain.

BIOLOGICAL CONTAMINANTS
Biological contaminants include bacteria, molds, mildew, viruses, animal dander and cat saliva, house dust mites, cockroaches, and pollen. There are many sources of these pollutants. Pollens originate from plants; viruses are transmitted by people and animals; bacteria are carried by people, animals, and soil and plant debris; and household pets are sources of saliva and animal dander. The protein in urine from rats and mice is a potent allergen. When it dries, it can become airborne. Contaminated central air handling systems can become breeding grounds for mold, mildew, and other sources of biological contaminants and can then distribute these contaminants through the home.

By controlling the relative humidity level in a home, the growth of some sources of biologicals can be minimized. A relative humidity of 30-50 percent is generally recommended for homes. Standing water, water-damaged materials, or wet surfaces also serve as a breeding ground for molds, mildews, bacteria, and insects. House dust mites, the source of one of the most powerful biological allergens, grow in damp, warm environments.

Health Effects From Biological Contaminants
Some biological contaminants trigger allergic reactions, including hypersensitivity pneumonitis, allergic rhinitis, and some types of asthma. Infectious illnesses, such as influenza, measles, and chicken pox are transmitted through the air. Molds and mildews release disease-causing toxins. Symptoms of health problems caused by biological pollutants include sneezing, watery eyes, coughing, shortness of breath, dizziness, lethargy, fever, and digestive problems.

Allergic reactions occur only after repeated exposure to a specific biological allergen. However, that reaction may occur immediately upon re-exposure or after multiple exposures over time. As a result, people who have noticed only mild allergic reactions, or no reactions at all, may suddenly find themselves very sensitive to particular allergens.

Some diseases, like humidifier fever, are associated with exposure to toxins from microorganisms that can grow in large building ventilation systems. However, these diseases can also be traced to microorganisms that grow in home heating and cooling systems and humidifiers. Children, elderly people, and people with breathing problems, allergies, and lung diseases are particularly susceptible to disease-causing biological agents in the indoor air.

STOVES, HEATERS, FIREPLACES, AND CHIMNEYS
In addition to environmental tobacco smoke, other sources of combustion products are unvented kerosene and gas space heaters, woodstoves, fireplaces, and gas stoves. The major pollutants released are carbon monoxide, nitrogen dioxide, and particles. Unvented kerosene heaters may also generate acid aerosols.

Combustion gases and particles also come from chimneys and flues that are improperly installed or maintained and cracked furnace heat exchangers. Pollutants from fireplaces and woodstoves with no dedicated outdoor air supply can be "back-drafted" from the chimney into the living space, particularly in weatherized homes.

Health Effects of Combustion Products
Carbon monoxide (CO) is a colorless, odorless gas that interferes with the delivery of oxygen throughout the body. At high concentrations it can cause unconsciousness and death. Lower concentrations can cause a range of symptoms from headaches, dizziness, weakness, nausea, confusion, and disorientation, to fatigue in healthy people and episodes of increased chest pain in people with chronic heart disease. The symptoms of carbon monoxide poisoning are sometimes confused with the flu or food poisoning. Fetuses, infants, elderly people, and people with anemia or with a history of heart or respiratory disease can be especially sensitive to carbon monoxide exposures.

Nitrogen dioxide (NO2) is a colorless, odorless gas that irritates the mucous membranes in the eye, nose, and throat and causes shortness of breath after exposure to high concentrations. There is evidence that high concentrations or continued exposure to low levels of nitrogen dioxide increases the risk of respiratory infection; there is also evidence from animal studies that repeated exposures to elevated nitrogen dioxide levels may lead, or contribute, to the development of lung disease such as emphysema. People at particular risk from exposure to nitrogen dioxide include children and individuals with asthma and other respiratory diseases.

Particles, released when fuels are incompletely burned, can lodge in the lungs and irritate or damage lung tissue. A number of pollutants, including radon and benzo(a)pyrene, both of which can cause cancer, attach to small particles that are inhaled and then carried deep into the lung.

HOUSEHOLD PRODUCTS
Organic chemicals are widely used as ingredients in household products. Paints, varnishes, and wax all contain organic solvents, as do many cleaning, disinfecting, cosmetic, degreasing, and hobby products. Fuels are made up of organic chemicals. All of these products can release organic compounds while you are using them, and, to some degree, when they are stored.

EPA's Total Exposure Assessment Methodology (TEAM) studies found levels of about a dozen common organic pollutants to be 2 to 5 times higher inside homes than outside, regardless of whether the homes were located in rural or highly industrial areas. Additional TEAM studies indicate that while people are using products containing organic chemicals, they can expose themselves and others to very high pollutant levels, and elevated concentrations can persist in the air long after the activity is completed.

Health Effects of Household Chemicals
The ability of organic chemicals to cause health effects varies greatly, from those that are highly toxic, to those with no known health effect. As with other pollutants, the extent and nature of the health effect will depend on many factors including level of exposure and length of time exposed. Eye and respiratory tract irritation, headaches, dizziness, visual disorders, and memory impairment are among the immediate symptoms that some people have experienced soon after exposure to some organics. At present, not much is known about what health effects occur from the levels of organics usually found in homes. Many organic compounds are known to cause cancer in animals; some are suspected of causing, or are known to cause, cancer in humans.